Cell-Based Research

FIND A CORE FACILITY TO HELP WITH YOUR RESEARCH

Search below to explore services, equipment, locations, and more

Please click on the core name for more details on the resources and expertise available in each.

Biointerfaces Institute (BI)

offers a suite of instrumentation capabilities that include 3D Bioprinting, Material and Particle Characterization and Rheology.

Sarah Spanninga, PhD
734-615-3758
bi-equipment@umich.edu

BRCF Advanced Genomics Core (AGC)

provides high-quality, low-cost advanced genomic analysis on a recharge basis.

Olivia Koues, PhD

advanced-genomics@umich.edu

BRCF Vector Core

produces biological vectors that facilitate the transfer of specific genes into either normal or aberrant cells.

Tom Lanigan, PhD
734-647-1351
lanigant@umich.edu

Bru-Seq Lab

provides nascent RNA sequencing using four techniques: Bru-seq, BruChase-seq, BruUV-seq, and BruDRB-seq.

Mats Ljungman, PhD
(734) 232-5438
BruseqCenter@umich.edu

Cardiovascular Regeneration Core Laboratory

generates patient-specific human induced pluripotent stem cells to study cardiovascular diseases.

Todd Herron, PhD
734-998-0460
cvcregenerationcore@gmail.com

Center for Chemical Genomics (CCG)

provides high-throughput screening of extensive small molecule, natural product and siRNA libraries.

Andrew Alt, PhD
734-763-2340
lsi-screening@umich.edu

Experimental Irradiation Core

specializes in moderate and low dose irradiation of cell cultures, tissues and animals.

Meredith Morgan, PhD
734-647-5928
mmccrack@umich.edu

Human Stem Cell and Gene Editing Core (HSCGE)

provides iPSC reprogramming, stem cell characterization and differentiation, and genome editing.

Wei Niu, PhD
734-615-8215
weiniu@med.umich.edu

Microbiome Core

provides microbial sequencing, high-throughput nucleic acid extraction, microbial cultivation, and strain identification.

Tom Schmidt, Ph.D

microbiomecore@umich.edu

Miller Lab

provides usage of the Agilent Seahorse XFe96 for cellular analysis of oxygen consumption and extracellular acidification.

Melissa Han
734-936-2164
melhan@med.umich.edu

Rogel Cancer Center Single Cell Analysis Resource

facilitates single cell experiments from initial experimental design through final data analysis.

Single Cell Analysis Resource

singlecellcorestaff@umich.edu

Single Molecule Analysis in Real-Time (SMART) Center

provides single molecule detection and manipulation tools to track and analyze biomolecules.

Damon Hoff, PhD
734-763-5449
hoffj@umich.edu

Total Cores: 12

Core Name	Equipment	Who We Serve
Biointerfaces Institute (BI)	3D Bioprinter 3DDiscovery, 3D printer Invivo, Chiral Raman Spectrometer Chiral RAMAN-2X, Circular Dichroism Spectrophotometer J-1700, Circular Dichroism Spectrophotometer J-815, Circularly Polarized Luminescence Spectrophotometer CPL-300, Differential Scanning Calorimeter Discovery DSC, Fluorometer FluoroMax Plus, Fluorometer QuantumMaster 400, Fourier-transform infrared spectrometer, Isothermal Titration Calorimetry Nano ITC, Liquid Differential Scanning Calorimeter Nano DCS, Live cell Holotomography 3D Cell Explorer Fluoro, Mercury Intrusion Porosimeter Autopore V (Model: 9620), Micromechanical Testing and Assembly Station FT-RS1002 Microrobotic System and FT-UMS1000 Universal Measurement Stand, Microscope with Live Cell environmental chamber IX83, Mueller Matrix Polarimeter Measurement System Exicor XZT, Nano Tensile/Compression Mechanical Tester UTM T150, Particle Size Characterization, Dynamic Light Scattering, Zeta Potential Zetasizer Nano ZSP, Particle Size Characterization, Laser Scattering Mastersizer 2000 with Hydro2000S, Particle Size Characterization, Nanoparticle Tracking Analysis Nanosight NS300, Particle Size Characterization, Nanoparticle Tracking Analysis, Zeta Potential ZetaView TWIN, Quantitative Pathology Microscope Workstation Mantra, Rheometer HR-2 Discovery Hybrid, Soft Material Mechanical Testing MicroSquisher, Superresolution Structured Illumination Microscopy ELYRA S.1 SIM, Surface Plasmon Resonance, Thermal Gravimetric Analysis Discovery TGA	University of Michigan Researchers and External Researchers
BRCF Advanced Genomics Core (AGC)	ABI qPCR System, Arrays iScan, Next Generation Sequencing, Next Generation Sequencing BluePippin, Next Generation Sequencing GridION, Next Generation Sequencing MiSeq, Next Generation Sequencing NextSeq 2000, Next Generation Sequencing NextSeq 500/550, Next Generation Sequencing NovaSeq 6000, Next Generation Sequencing S2, Quality Control 2200 TapeStation, Quality Control 4200 TapeStation, Quality Control Bioanalyzer, Quality Control LabChip GX Touch, Quality Control Qubit Fluorimeter, Single Cell Chromium Controller, Single Cell Chromium System, Single Cell ChromiumX, Single Cell Countess II, Single Cell Luna Fx7, Spatial Transcriptomics CM1860, Spatial Transcriptomics Epifluorescence Microscope BX51, Spatial Transcriptomics GeoMx DSP, Spatial Transcriptomics S700, Spatial Transcriptomics Visium CytAssist, qPCR QuantSTudio 12K Flex, qPCR StepOne	University of Michigan Researchers and External Researchers
BRCF Vector Core		University of Michigan Researchers and External Researchers
Bru-Seq Lab		University of Michigan Researchers and External Researchers
Cardiovascular Regeneration Core Laboratory	Biosafety cabinets, Controlled rate freezer, Incubators, Incucyte Zoom, Inverted, Isothermic liquid nitrogen storage tank, MACS Quant VYB flow cytometer	University of Michigan Researchers and External Researchers
Center for Chemical Genomics (CCG)	Biomek FX96 & 384, Echo 655 Liquid Handler, Flow Cytometer, Image Express Micro (IXM), Mosquito, MultiDrop Combi, MultiDrop Nano, Pintool Biomek FX, Pintool Sciclone ALHD 3000, Plate reader, Plate reader Envision, Plate reader FDSS 7000, Plate washer Biotek EL 406, Plate washer Biotek ELX405, SyncroPatch 384, Tissue Culture Room	University of Michigan Researchers and External Researchers
Experimental Irradiation Core	Metered isoflurane, MicroPoint, Orthovoltage IC225, Orthovoltage unit, Small Animal Radiation Research Platform (SARRP)	University of Michigan Researchers and External Researchers
Human Stem Cell and Gene Editing Core (HSCGE)	Biosafety cabinet, Centrifuge Sorval ST8, Countess FL, ECO CLEANBENCH, EVOS FL Auto live imaging system, Heraeus CO2 tissue culture incubators, IncuCyte living-cell analysis system, Inverted CKX53 microscope with LED illumination, Laminar workflow station, Multiple electrode array, NEON transfection system, Tissue incubator with high-O2 capacity, Tissue incubator with low-O2 capacity	University of Michigan Researchers and External Researchers
Microbiome Core	ABI qPCR System, Agilent BioAnalyzer, Anaerobic Growth Chambers - Hypoxic & Anaerobic COY Chambers, Axygen Gel Documentation System, Bruker MALDI Biotyper Sirius GP System, Class II biological cabinets, Eppendorf Mastercyclers, Eppendorf epMotion, Illumina MiSeq, Qiagen TissueLyser II	University of Michigan Researchers, External Researchers
Miller Lab	Agilent Seahorse XFe96 Analyzer	University of Michigan Researchers
Rogel Cancer Center Single Cell Analysis Resource	Biomark, C1, Chromium, Tapestri	University of Michigan Researchers and External Researchers
Single Molecule Analysis in Real-Time (SMART) Center	MiniTweezers Optical Tweezers, Single Particle Nanomanipulator, Optical Tweezers and Fluorescence Microscope, Single Particle Tracker TIRF/HILO Fluorescence Microscope (plus cellTIRF and accessories) IX81, Table-top Atomic Force Microscope TT-AFM, Time-Resolved Confocal Microscope Alba-5	University of Michigan Researchers and External Researchers

Total Cores: 12

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1018 Fuller Street
777 Building
AATBSRB
Brehm
BSB
Cancer Center
Chem
Clark Library
Commonwealth
CVC
Dentistry
Domino's Farms
Duderstadt Center
East Hall
EECS
Herbarium
ISR-Perry
ISR-Thompson
Liberty Bldg
Mary Sue Coleman Hall
Mcity
Michigan Memorial Phoenix Laboratory
MS II
MSI
MSRB I
MSRB II
MSRB III
NCRC Bldg 14
NCRC Bldg 16
NCRC Bldg 20
NCRC Bldg 22
NCRC Bldg 25
NCRC Bldg 26
NCRC Bldg 35
NCRC Bldg 400
NCRC Bldg 520
NCRC Bldg 60
NIB
NUB
Perry Building
Pharmacy
Rachel Upjohn Bldg
Rackham Bldg
Randall Lab
Ross School of Business
Shapiro Library
SOE
SPH I
SPRL
Taubman Health Sciences Library
UH
UMTRI