Microbiome Core

provides microbial sequencing, high-throughput nucleic acid extraction, microbial cultivation, and strain identification.


Tom Schmidt, Ph.D



MSRB I (Rm 1500)
1150 W. Med Center Drive, Ann Arbor, MI

Medical School

Who We Serve

University of Michigan Researchers, External Researchers

Core Summary

The Microbiome Core supports a large set of internal and external clientele with their microbial research studies. We are located in the Medical Science Research Building I (MSRB 1), on the Medical Campus. We offer microbial community profiling (16S / ITS), RNA-seq, and whole-genome sequencing. Library generation can be carried out on specimens from a variety of sources, including swabs, tissue, soil, microbial cultures, and fecal samples. The processing of high-throughput sample sets is automated using epMotion liquid handlers. Libraries are sequenced on the Illumina MiSeq platform.

The core will soon be working with the GI Center’s Microbial Interactions Core to offer a platform for co-culturing microbes with host tissues, strain identification using a MALDI Biotyper and a culture collection.  If you are interested in any of these services, please visit our website to learn more: https://microbe.med.umich.edu/welcome-university-michigan’s-microbiome-core. We provide reliable results with fast turnover and are always looking to expand our client base.

Service Categories: Cell-Based Research; Gene Sequencing, Expression and Analysis ; Molecular Biology


  • Electrophoresis
    Agilent BioAnalyzer,

  • Microbial Coculturing

  • Microbial Sequencing – 16S rDNA/ITS/EMP community profiling

  • Microbial Strain Identification

  • Nucleic acid extraction

  • RNA Sequencing

  • Whole Genome Sequencing - Small Genomes


  • ABI qPCR System
    Applied Biosystems, Core Use only
  • Agilent BioAnalyzer
  • Anaerobic Growth Chambers - Hypoxic & Anaerobic COY Chambers
  • Axygen Gel Documentation System
  • Bruker MALDI Biotyper Sirius GP System
  • Class II biological cabinets
  • Eppendorf epMotion
  • Eppendorf Mastercyclers
  • Illumina MiSeq
  • Qiagen TissueLyser II