Experimental Irradiation Core

specializes in moderate and low dose irradiation of cell cultures, tissues and animals.


David Karnak, PhD

Meredith Morgan, PhD


Med Sci I (Rm 4310 & 3504E)
1301 E. Catherine St, Ann Arbor, MI

BSRB (Rm D714)
109 Zina Pitcher Pl, Ann Arbor, MI

NCRC Building 26 (Rm G11N)
2800 Plymouth Rd, Ann Arbor, MI

Medical School

Who We Serve

University of Michigan Researchers and External Researchers

Core Summary

The Experimental Irradiation Core specializes in moderate dose (0.1-4 Gy/min) and low dose irradiation (0.05-0.3 Gy/hr) of cell cultures, tissues, and animals.

The specific goals of the Irradiation Core are to:

  • Support studies in the radiation biology of moderate dose rate irradiation of cell cultures and small animals, such as mice, rats, and rabbits.
  • Permit the study of low-dose rate irradiation in cell culture.
  • Provide irradiation services for investigators whose primary interests are not in radiation biology, but who need this tool in support of other efforts (for example, immunosuppression of animals prior to stem cell transplantation through total body irradiation).
  • Facilitate study of the cellular responses to DNA damage utilizing laser microirradiation as a tool.
  • Provide state-of-the-art CT and bioluminescence imaging-based radiation delivery to animals.

Service Categories: Animal Research; Cell-Based Research


  • 3D imaging via cone beam CT

  • 3D treatment planning with conformal radiation delivery

  • Animal anesthesia during irradiation

  • Bioluminescent tumor detection for treatment guidance

  • Irradiation
    Laser micro-irradiation, Low dose, Moderate dose,


  • Metered isoflurane
  • MicroPoint
  • Orthovoltage IC225
    Kimtron, Available for Use
  • Orthovoltage unit
    Kimtron, Available for Use
  • Small Animal Radiation Research Platform (SARRP)