Cardiovascular Regeneration Core Laboratory

generates patient-specific human induced pluripotent stem cells to study cardiovascular diseases.


Todd Herron, PhD


NCRC Building 26 (Rm 215N)
2800 Plymouth Rd, Ann Arbor, MI

Medical School

Who We Serve

University of Michigan Researchers and External Researchers

Core Summary

The Cardiovascular Regeneration Core Laboratory routinely generates patient-specific human induced pluripotent stem cells (hiPSCs) for basic science research purposes of cardiovascular diseases. We generate chamber specific human cardiac cells (atrial vs. ventricular) for basic research, drug discovery, cardiotoxicity and personalized medicine. Healthy control as well as diseased human cardiac cells are available for transfer to UM laboratories for use in basic science research.

Service Categories: Cell-Based Research; Data Tools and Analysis ; Imaging


  • 3D microtissue generation and force measurements

  • Cardiac directed differentiation

  • Cryobanking/storage of patient cells

  • Differentiation to vascular cells

  • Drug Discovery screening for cardiotoxicity and proarrhythmia

  • Electrophysiological phenotype analysis

  • Fibroblast expansion

  • hiPSC-CM purification

  • Maintenance and characterization of iPSCs

  • Reprogramming to iPSCs


  • Biosafety cabinets
  • Controlled rate freezer
  • Incubators
  • Incucyte Zoom
  • Inverted
  • Isothermic liquid nitrogen storage tank
  • MACS Quant VYB flow cytometer