Cardiovascular Regeneration Core Laboratory

generates patient-specific human induced pluripotent stem cells to study cardiovascular diseases.

Contacts

Todd Herron, PhD
734-998-0460
cvcregenerationcore@gmail.com

Location

NCRC Building 26 (Rm 215N)
2800 Plymouth Rd, Ann Arbor, MI

Affiliations
Medical School

Who We Serve

University of Michigan Researchers and External Researchers

Core Summary

The Cardiovascular Regeneration Core Laboratory routinely generates patient-specific human induced pluripotent stem cells (hiPSCs) for basic science research purposes of cardiovascular diseases. We generate chamber specific human cardiac cells (atrial vs. ventricular) for basic research, drug discovery, cardiotoxicity and personalized medicine. Healthy control as well as diseased human cardiac cells are available for transfer to UM laboratories for use in basic science research.

Service Categories: Cell-Based Research Service Categories: Data Tools and Analysis Service Categories: Imaging

Services

3D microtissue generation and force measurements

Cardiac directed differentiation

Cryobanking/storage of patient cells

Differentiation to vascular cells

Drug Discovery screening for cardiotoxicity and proarrhythmia

Electrophysiological phenotype analysis

Fibroblast expansion

hiPSC-CM purification

Maintenance and characterization of iPSCs

Reprogramming to iPSCs


Equipment

Biosafety cabinets

Controlled rate freezer

Incubators

Isothermic liquid nitrogen storage tank

Live-Cell Analysis
Incucyte Zoom,

Microscope
Inverted,