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Advanced Research Computing at the University of Michigan provides researchers with high-performance computing resources, secure data storage, and specialized support to enable complex data analysis, simulations, and computational research. These services help faculty, staff, and students accelerate scientific discovery and innovation across diverse academic disciplines.
Services
Data Tools and Analysis, Education and Training, Engineering, Informatics, Statistics & Computation
Serving:
U-M Researchers
Affiliation:
Information Technology Services
AI&DHI supports AI research at U-M by providing researchers with access to rich health data for retrospective and prospective studies and model validation, compute and storage resources, and research faciltation services to advance health research from ideation to clinical implementation.
Serving:
U-M Researchers
Affiliation:
Medical School, College of Engineering, School of Public Health
Provides access for researchers to appropriate laboratory facilities to conduct non-Select Agent in-vivo work.
Serving:
U-M Researchers
Affiliation:
Medical School
Performs a variety of in vivo physiologival assessments and behavioral measurements.
Serving:
External Researchers
U-M Researchers
Affiliation:
Medical School
Facilities are available for investigators to perform sterile, minimally-invasive, and non-sterile surgical procedures on both small and large animals. Services and facilities can be utilized individually or combined as a full service based on the needs of a specific research project. Facility personnel are licensed veterinary technicians and a ULAM Veterinary Board-Certified Surgeon oversees daily operations.
Serving:
U-M Researchers
Affiliation:
Medical School
The Nanotechnicum is a Biointerfaces Institute core facility providing Nanoparticle Size analysis and Zeta Potential characterization, Chiral materials spectroscopy, Material Pore Size and Porosity characterization, Materials Thermal analysis, and Biomolecular Binding characterization instrumentation and services. The Biointerfaces Institute offers instrumentation to the University of Michigan’s research community, fellow academic institutions, and industry.
Serving:
External Researchers
U-M Researchers
Affiliation:
Biointerfaces Institute
The Biomolecular Nuclear Magnetic Resonance (Biomolecular NMR) Laboratory uses state of the art NMR instruments, providing the ability to obtain structural, dynamic and kinetic information on biological macromolecules including protein, RNA and DNA. Automated sampling devices also make it ideal for metabolomics and high throughput data collection.
Services
Chemical Characterization, Data Tools and Analysis, Drug Discovery & Pharmacology, Imaging, Microscopy, and Analysis, Nuclear Magnetic Resonance Spectroscopy, Nucleic Acids
Serving:
External Researchers
U-M Researchers
Affiliation:
College of Literature, Science & the Arts
The Advanced Genomics Core is well-known for their “next-generation” sequencing (NGS), which has revolutionized research in virtually all biological fields in the past decade. By housing NGS and companion genomic technologies in a single facility, we provide centralized expertise in advanced methods that enables all researchers to effectively exploit them for making scientific discoveries.
Services
Cancer Research, Cell-Based Research, Histology, Pathology, & Tissue, Human Research, Molecular Biology, Nucleic Acids, Single Cell & Spatial Analysis, Stem Cell
Serving:
External Researchers
U-M Researchers
Affiliation:
Medical School
The Bioinformatics Core helps researchers identify and interpret patterns in RNA and DNA by placing sequencing data into a biologically meaningful context. This includes assisting with experimental design, developing reproducible workflows, analyzing next-generation sequencing data, supporting manuscript development/publication, and hosting regular workshops on bioinformatics analysis.
Services
Cancer Research, Data Tools and Analysis, Human Research, Informatics, Statistics & Computation, Mass Spectrometry, Molecular Biology, Nucleic Acids
Serving:
External Researchers
U-M Researchers
Affiliation:
Medical School
The Epigenomics Core provides resources and services to prepare samples for analysis in epigenetic regulation in both genome-wide and locus-specific manners. We provide sample quality control, library preparation and sequencing for the study of cytosince and histone modifications
Serving:
External Researchers
U-M Researchers
Affiliation:
Medical School
The Flow Cytometry Core provides instrumentation and expertise to University of Michigan investigators – and the surrounding biotech community – in a broad range of basic and medical science disciplines. Samples are prepared by individual investigators, who then deliver samples to the Core for flow cytometric analysis or cell sorting. The Core also provides assistance in grant and publication preparation, publication-quality graphics, and development of experimental designs.
Serving:
External Researchers
U-M Researchers
Affiliation:
Medical School
The Microscopy Core offers support and training on a variety of high-end instrumentation and advanced methodologies for both light and electron microscopy.
Services
Assay Development, Cancer Research, Cell-Based Research, Data Tools and Analysis, Education and Training, Histology, Pathology, & Tissue, Imaging, Microscopy, and Analysis, Neuroscience, Physiology, Protein, Stem Cell
Serving:
External Researchers
U-M Researchers
Affiliation:
Medical School
The goal of the PRF is to assist researchers in designing proteomic experiment, maintain state-of-the-art instrumentation, provide technical expertise and bioinformatic support during both discovery and validation phases of proteomic experiments.
Serving:
External Researchers
U-M Researchers
Affiliation:
Medical School
Providing U-M research investigators with easy, on-site procurement of enzymes, reagents, and kits used in molecular work, and cell biology with four locations across campus.
Serving:
U-M Researchers
Affiliation:
Medical School
provide access to transgenic animal technology in an efficient, effective manner.
Services
Animal Research, Cancer Research, Cell-Based Research, Education and Training, Molecular Biology, Nucleic Acids
Serving:
External Researchers
U-M Researchers
Affiliation:
Medical School
The University of Michigan Bru-seq Lab is a core facility that provides nascent RNA sequencing using four techniques: Bru-seq, BruChase-seq, BruUV-seq, and BruDRB-seq. This service is all-inclusive, starting with cells and ending with basic data analysis. In addition, users will have access to our exclusive pipeline to perform further data analysis.
Serving:
External Researchers
U-M Researchers
Affiliation:
Center for RNA Biomedicine
The Center for Chemical Genomics provides high-throughput screening of extensive small molecule, natural product and siRNA libraries — along with assay development and optimization — for basic biology and drug discovery projects. Our dedicated staff has years of experience in academic drug discovery and within the pharmaceutical industry, allowing us to provide expert guidance to researchers through every stage of a project.
Services
Assay Development, Cancer Research, Cell-Based Research, Data Tools and Analysis, Drug Discovery & Pharmacology, Education and Training, Flow Cytometry, Imaging, Microscopy, and Analysis, Informatics, Statistics & Computation, Phenotyping
Serving:
External Researchers
U-M Researchers
Affiliation:
Life Sciences Institute
The Center for Molecular Imaging and Preclinical Molecular Imaging are state-of-the-art facilities aimed at providing the research community with the latest imaging Instruments. These facilities offer a diverse range of imaging systems, including in vivo bioluminescent/fluorescent imaging and bioluminescent/fluorescent/CT systems, a Bruker 7-Tesla horizontal bore MRI system, a 4DMedical Permetium lung function CT system and a 3T-MRI system.
Serving:
External Researchers
U-M Researchers
Affiliation:
Medical School
The Center for Structural Biology is a comprehensive structural biology resource for researchers at the University of Michigan and beyond. Part of the U-M Life Sciences Institute, the CSB includes: a high-throughput protein laboratory for protein engineering, protein purification facilities for small- and large-scale protein production, macromolecular crystallization and crystallography laboratories for solving crystal structures of biological molecules, an X-ray facility with access to high energy synchrotron radiation.
Services
Cancer Research, Chemical Characterization, Drug Discovery & Pharmacology, Mass Spectrometry, Molecular Biology, Protein
Serving:
External Researchers
U-M Researchers
Affiliation:
Life Sciences Institute
The Central Biorepository (CBR) is a recharge-based core facility supporting collaboration among University of Michigan Medical School (UMMS) investigators by streamlining human biospecimen access, handling, processing, and compliance to accelerate biomedical research. Its services include:
• Access to Biospecimens and Data: Researchers have access to hundreds of thousands of human biospecimens, each carefully annotated with clinical and research data.
• Specimen Management: The CBR provides secure, monitored, and CAP-accredited storage for participating clinical research study teams using a Laboratory Information Management System (LIMS), LabVantage, for full traceability, data integration, and reporting.
• Processing Services: Automated laboratory processing is performed using standardized and validated protocols to ensure specimen quality and reproducibility.
• Collection Kit Logistics: For those participating clinical research study teams collecting human specimens, the CBR creates and ships custom specimen collection kits and coordinates biospecimen logistics.
• Distribution and Shipping: The CBR manages controlled distribution and shipping of biospecimens to researchers and their collaborators as needed.
• Regulatory Support: Assistance is provided for regulatory submission preparation to ensure compliance in research projects.
Services
Biorepository, Cancer Research, Cell-Based Research, Histology, Pathology, & Tissue, Human Research, Nucleic Acids
Serving:
U-M Researchers
Affiliation:
Medical School
Research support lab for studies conducting biospecimen collections and molecular biomarker research. We offer custom designed biospecimen collection kits, logistic support for biospecimen collections, a BAP accredited biorepository to store specimens in, and a variety of assay services.
Serving:
External Researchers
U-M Researchers
Affiliation:
School of Public Health