BRCF Transgenic Animal Model Core
provide access to transgenic animal technology in an efficient, effective manner.
RRID
copy/paste for citations
University of Michigan BRCF Transgenic Animal Model Core RRID:SCR_000776
Serving
External Researchers, U-M Researchers
Service Categories
Animal Research, Cancer Research, Cell-Based Research, Education and Training, Molecular Biology, Nucleic Acids
Services
- Production of transgenic mice
- CRISPR/Cas9 mediated genome editing in mice and rats
- Production of transgenic rats
- Zinc finger nuclease gene knockout and knockin rats
- Production of gene-targeted mouse embryonic stem (ES) cells for mouse knockout models and in vitro studies
- Production of ES cell-mouse chimeras for mouse knockout models
- Assisted reproduction technology for mice and rats
- De novo derivation of mouse ES cells from custom mice
- Hands-on training in mouse ES cell manipulation, pronuclear microinjection, and blastocyst injection