Center for Structural Biology

The Center for Structural Biology is a comprehensive structural biology resource for researchers at the University of Michigan and beyond. Part of the U-M Life Sciences Institute, the CSB includes: a high-throughput protein laboratory for protein engineering, protein purification facilities for small- and large-scale protein production, macromolecular crystallization and crystallography laboratories for solving crystal structures of biological molecules, an X-ray facility with access to high energy synchrotron radiation.

RRID

copy/paste for citations

University of Michigan Center for Structural Biology RRID:SCR_021065

Serving

External Researchers, U-M Researchers

Service Categories

Cancer Research, Chemical Characterization, Drug Discovery & Pharmacology, Mass Spectrometry, Molecular Biology, Protein

Contact

Jeanne Stuckey

[email protected]

Affiliation

Life Sciences Institute

CFMS Website

Services

  • High-Throughput Cloning & Expression Testing
  • Protein expression in E. coli, Baculovirus, Mammalian and Yeast Cells
  • Protein Purification
  • Macromolecular Crystallization & Crystallography
  • Biophysical Characterization of Ligand Binding
  • Mass Spectrometry

Equipment

  • Octet Red System
  • KingFisher QPCR Machine
  • Mass Photometer
  • SEC-MALS System
  • Crystallization Robot
  • X-Ray Diffraction System
  • AKTA FPLC (x2)
  • Variable Temp Floor Shaker/Incubator (x3)
  • Table Top Variable Shaker/Incubator (x2)
  • Variable Temp Incubator
  • High-Pressure Microfluidizer
  • QTOF and TOF
  • Nanodrop