Microscopy and Image Analysis Core (MIAC) of the Michigan Diabetes Research Center (MDRC). The MIAC provides state-of-the-art protein and RNA imaging to enhance the diabetes-related research at the University of Michigan. The MIAC provides expertise, advice training and equipment for microscopic and morphometric analysis of both protein and RNA in biologic samples in support of research focused on diabetes and its complications or related endocrine and metabolic disorders. The MIAC provides access to a wide variety of microscopy and imaging equipment that otherwise would be beyond the scope and resources of most investigators. The overwhelming majority of MDRC investigators who require such techniques rely on the MIAC to provide them and their staff with expert consultation, training and support for routine and advanced microscopy and image analysis for protein and RNA morphometric studies.