Human Stem Cell Gene Editing Core
The HSCGE core is dedicated to provide neuroscience research community valuable new sources of human pluripotent stem cells (hPSCs) for basic research, drug discovery, or cell therapy. We offer a wide-range of services including but not limited to derivation of induced pluripotent stem cells (iPSCs) from fibroblasts or blood cells, CRISPR/Cas9-mediated gene editing hPSCs, and training for hPSC maintenance.
RRID
copy/paste for citations
University of Michigan Human Stem Cell Gene Editing Core RRID:SCR_026755
Serving
External Researchers, U-M Researchers
Service Categories
Cell-Based Research, Clean Room, Human Research, Imaging, Microscopy, and Analysis, Molecular Biology, Neuroscience, Stem Cell
Services
- Derivation of iPSCs from fibroblasts
- Derivation of iPSCs from blood cells
- CRISPR gene ablation in hES or hiPSC (KO)
- CRISPR HDR in hES or hiPSC (KI)
- 2 weeks stem cell training
- Core lab usage
- Incucyte usage
- Neon usage
- Control iPSC lines
Equipment
- EVOS M7000
- Incucyte
- Stereo microscope with Thermoplate
- Inverted Microscope
- Neon NxT