Biomolecular Nuclear Magnetic Resonance Laboratory
uses state of the art NMR instruments to obtain structural, dynamic and kinetic information on biological macromolecules.
Contacts
Debashish Sahu, PhD
734-647-3872
bionmrcore@umich.edu
Location
Chemistry Building (Rm 1047 & 2060)
930 N. University Ave, Ann Arbor, MI
Mary Sue Coleman Hall (LSI - Rm 3214)
210 Washtenaw Ave, Ann Arbor, MI
Literature, Science and the Arts
Who We Serve
University of Michigan Researchers and External Researchers
Core Summary
The Biomolecular Nuclear Magnetic Resonance (Biomolecular NMR) Laboratory uses state of the art NMR instruments, providing the ability to obtain structural, dynamic and kinetic information on biological macromolecules including protein, RNA and DNA. Automated sampling devices also make it ideal for metabolomics and high throughput data collection.
Services
- Dynamics of biomolecules
- Monitoring drug stability over time
- NMR
One-on-one training on NMR operation and data interpretation,
- Protein, RNA and DNA structure elucidation
- Quantitation of soluble materials
- Real-time kinetics reaction monitoring
- Structure analysis report
- Structure identification of drug metabolites, impurities, degradants and unknowns
- Study of dynamics and structure of drug-receptor interactions
- Verification of structures of drugs and reference compounds
Equipment
- Agilent/Varian 400 MHz w/room temperature probe (H/F-X) 400 MHz NMR
Bruker, Equipment Available For Use - Bruker 600 MHz w/cryoprobe (H/C/N) 600MHz NMR
Bruker, Equipment Available For Use - Bruker 600 MHz w/prodigy cryoprobe (H/F-X) 600 MHz NMR
Bruker, Equipment Available For Use - Bruker 800 MHz w/cryoprobe (H/C/N) 800MHz NMR
Bruker, Equipment Available For Use