Established in 2004, the germ-free mouse facility, part of the Unit for Laboratory Animal Medicine (ULAM), provides services to the entire University of Michigan community and can also ship germ-free mice to locations worldwide.

Primary and collaborative research projects include studies investigating inflammatory bowel disease and cancer, host microbiome interactions, infectious disease pathogenesis, and mammalian and bacterial metabolism, among others. The staff also performs research and training in gnotobiotic technology and methods.