Biomolecular Nuclear Magnetic Resonance Core
The Biomolecular Nuclear Magnetic Resonance (Biomolecular NMR) Laboratory uses state of the art NMR instruments, providing the ability to obtain structural, dynamic and kinetic information on biological macromolecules including protein, RNA and DNA. Automated sampling devices also make it ideal for metabolomics and high throughput data collection.
RRID
copy/paste for citations
University of Michigan Biomolecular Nuclear Magnetic Resonance Core RRID:SCR_026719
Serving
External Researchers, U-M Researchers
Service Categories
Chemical Characterization, Data Tools and Analysis, Drug Discovery & Pharmacology, Imaging, Microscopy, and Analysis, Nuclear Magnetic Resonance Spectroscopy, Nucleic Acids
Services
- Training
- Project Consultation
- Custom NMR Experiments
- Automation
- Data Processing
- Sample Prep Consultation
- Data Analysis
- Dynamics of Biomolecules
- Monitoring Drug Stability Over Time
- Protein, RNA, and DNA Structure Elucidation
- Quantitation of Soluble Materials
- Real-time Kinetics Reaction Monitoring
- Structure Analysis Report
- Structure Identification of Drug Metabolites, Impurities, Degradants and Unknowns
- Study of Dynamics and Structure of Drug-Receptor Interactions
- Verification of Structures of Drugs and Reference Compounds
- Metabolomics Analysis
- Ligand Screening (Fragment-Based Drug Discovery)
- Temperature-Dependent Studies
- Diffusion NMR (DOSY)
Equipment
- 800 MHz NMR
- 600 MHz NMR
- 600 MHz NMR
- 400 MHz NMR